Anaheim, CA -- (Sports Network) - Vladimir Guerrero homered and drove in four runs, as the Angels downed the Chicago White Sox, 10-7, in the opener of a four-game series.

Nick Adenhart (1-0), making his third career start, gave up nine hits and four runs in 5 2/3 innings to earn his first major league win. Following the game, the club sent Adenhart back to Triple-A Salt Lake.

"It feels good to get my first win," Adenhart said. "I had a rough start and I feel I'm heading in the right direction."

Garret Anderson was 3-for-4 with a run scored and an RBI for the Angels, who snapped a season-high four-game losing streak. Gary Matthews Jr. and Erick Aybar both had two hits and drove in a run.

Mark Buehrle (1-5) took the loss after yielding eight runs -- six earned -- on 10 hits in 5 2/3 innings for Chicago, which has dropped two straight.

Jermaine Dye finished 4-for-5 and scored two runs in his 1,500th career game, while Joe Crede went 2-for-2 with a walk and two RBI. Juan Uribe drove in two runs. A.J. Pierzynski doubled twice, scored twice and knocked in a run.

A two-out RBI single by Crede made it a 4-2 game in the fourth, but the Angels pulled ahead with four runs in the fifth. Sean Rodriguez and Matthews singled to start the inning before Guerrero crushed a three-run homer to give LA its first lead of the game. Anderson added an RBI triple later in the frame.

"You take that one pitch away from Vlad and we win the game," Buehrle said. "It's frustrating. You can't complain. It all evens out. I hope it starts to even out soon."

Los Angeles widened its margin with four runs in the sixth. A costly two-out throwing error by Crede on a ball hit by Matthews extended the inning. Aybar then stroked a double to left field to plate Matthews and Guerrero followed with a run-scoring single. Casey Kotchman followed a hit by Torii Hunter with a two-run, pinch single to give the Angels a 10-4 lead.

Consecutive doubles by Dye and Pierzynski to start to eighth resulted in a run and, after Nick Swisher flied out, Pierzynski came around to score on an infield single from Alexei Ramirez.

Chicago picked up another run in the ninth on a groundout by Pablo Ozuna, but Francisco Rodriguez recorded the final two outs to notch his 15th save of the season.

The White Sox jumped out to a 3-0 lead in the second. A one-out single by Dye followed by a walk to Pierzynski and a base hit from Swisher loaded the bases for Crede, who reached on an infield single. Uribe then ripped a two-run single to center field.

Los Angeles scored two runs in the next frame. A leadoff walk to Robb Quinlan and a single by Anderson put runners on the corners for Mike Napoli, who hit a sacrifice fly to put the Angels on the board. Two batters later, Matthews lined a single to left field to plate Anderson.

Game Notes

Buehrle has lost his last five decisions...Chicago left eight men on base, while the Angels stranded six...Prior to the game, the Angels recalled infielder Matt Brown from Salt Lake (PCL) and optioned infielder Brandon Wood to Salt Lake...Chicago won five of its nine matchups with the Angels last season and is 11-7 in the series since the start of the 2006 campaign...Chicago's John Danks (3-3) will be opposed by LA's Jered Weaver (2-5) on Tuesday.