The accident also claimed the life of the wrong-way driver who died as his pickup truck was engulfed in flames.
This crash was the latest in what some see as a rash of wrong-way driver fatal collisions in which more than a dozen people have died in Northern California in the past three months.
"I'm sad. I'm frustrated. I'm angry," said Democratic Assemblyman Freddie Rodriguez from Pomona.
Rodrigues is attempting to fast track his bill that would require Caltrans and the California Highway Patrol to study wrong way driving incidents and look to other states of possible solutions.
Caltrans says it is already looking into possible solutions by modifying "Wrong Way" signs at highway off-ramps.
"We can put lights on there that are triggered by wrong-way movements," said Caltrans Director Malcolm Dougherty. "We can also put a warning system on there that notifies law enforcement."
But, Dougherty warns that California has thousands of off-ramps. He says all options are being considered as the problem is studied.
According to the latest report from the National Traffic Safety Bureau, 69 percent of wrong way drivers have a blood alcohol content greater than the legal limit.