49ers getting Samuel, possibly other key players back

Receiver Deebo Samuel has been cleared to return for Sunday’s game against the Los Angeles Rams after missing the past three games with a hamstring injury.

San Francisco braces for fall back to most restrictive tier

San Francisco is poised to fall into the purple tier as the city's COVID numbers reach dangerous heights.

Jimmy Garoppolo's future remains questionable for 49ers

The 49ers (4-6) head into their bye week on the fringe of the NFC playoff race, which could make the biggest drama down the stretch be how Garoppolo looks heading into the offseason.

49ers claim McKinley off waivers, place Kinlaw on COVID list

Defensive lineman Arik Armstead went on the list earlier this week after a positive test and the team was conducting contact tracing to determine if anyone else needed to go on it as well.

Shanahan: Niners 'blew an opportunity' vs surging Saints

“If we had taken care of the ball better today, we would have had a very good chance to be in that game,” coach Kyle Shanahan said

AP source: NFL probe 49ers for possible COVID violations

A person familiar with the investigation says the probe is looking into whether Bourne was wearing a face covering as required by the COVID-19 rules.

Aaron Rodgers leads Packers past undermanned 49ers, 34-17

The lone bright spot for the 49ers was the performance of receiver Richie James Jr., who had nine catches for 184 yards and a TD.

Big days from Wilson, Metcalf lead Seahawks past 49ers 37-27

Wilson and Metcalf tormented San Francisco and its banged up secondary as the top-scoring offense in the league continued to pile up points.

49ers activate RB Coleman, CB Williams from IR

The Niners also placed running back Jeff Wilson Jr. on injured reserve with a high ankle sprain and activated receiver River Cracraft and safety Johnathan Cyprien from the practice squad on Saturday.

Seahawks host 49ers in another key NFC West showdown

Seattle took its first loss of the season last week in a 37-34 overtime setback to Arizona.

49ers crush Patriots 33-6

49ers quarterback Jimmy Garoppolo finished 20 of 25 for 277 yards with two interceptions in his first game against his former team.

49ers place Mostert on IR, add 2 safeties to roster

Mostert went down with a high ankle sprain last week against the Rams and will miss a few weeks.

Thinking of 49ers, Edelman has 'Jerry Rice Hill' to thank

Edelman dated Rice’s daughter, Jaqui, in high school and took her to the prom, but that's not why he was shy around her father.

Garoppolo, 49ers hope to add to Patriots' recent woes

Garoppolo now returns Sunday to face his former team for the first time since being traded to San Francisco (3-3) in 2017.

Santa Clara County decides no audiences allowed at Levi’s Stadium

Football fans hoping to see the 49ers in person won't be able to just yet. On Tuesday, leaders in Santa Clara County said they are not going to follow the state’s new guidance for stadiums.